Metabolic syndrome is a clustering of interrelated cardiometabolic risk factors that together substantially raise the likelihood of cardiovascular disease and type 2 diabetes. The defining components are central, abdominal obesity, elevated triglycerides, reduced high-density lipoprotein cholesterol, raised blood pr…
Metabolic syndrome is a clustering of interrelated cardiometabolic risk factors that together substantially raise the likelihood of cardiovascular disease and type 2 diabetes. The defining components are central, abdominal obesity, elevated triglycerides, reduced high-density lipoprotein cholesterol, raised blood pressure, and impaired glucose regulation reflecting insulin resistance or hyperglycemia. These features tend to co-occur, and their combination confers greater risk than any single factor alone, which is why the syndrome is treated as an integrated clinical entity rather than a set of isolated abnormalities. Insulin resistance and dysfunctional adipose tissue are widely regarded as central to its pathophysiology, linking excess and ectopic fat to disturbances in lipid metabolism, blood pressure, and glycemic control. Research in this area addresses prevalence and risk factors across occupational and clinical groups, the molecular and metabolic pathogenesis underlying associated dyslipidemias, and anthropometric indicators of central obesity used to gauge metabolic risk. A substantial body of work examines dietary and nutritional influences, including the effects of specific foods, antioxidant micronutrients, and other supplements on insulin sensitivity, lipemia, and glycemia, as well as connections to diabetes and to medication-related metabolic effects. By characterizing how these elements interact, study of metabolic syndrome informs prevention, risk stratification, and lifestyle and nutritional strategies aimed at reducing long-term cardiometabolic harm.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Metabolic Syndrome, linking to each citing work.