Overview
A cervical biopsy is a diagnostic procedure in which a small sample of tissue is removed from the cervix and examined microscopically to detect, characterize, or exclude precancerous and cancerous change. It is typically performed after an abnormal screening result, such as cytological atypia on a cervical smear or a positive human papillomavirus test, and is often directed by colposcopy so that suspicious areas are sampled accurately. Histopathological examination of the biopsy establishes whether the epithelium shows dysplasia, the grade of any intraepithelial lesion, or invasive carcinoma, and thereby guides decisions about surveillance, excisional treatment, or further management. Within Cervical Cancer care, biopsy provides the definitive tissue diagnosis that screening alone cannot supply, situated along a pathway that links screening uptake, abnormal cytology, and confirmatory pathology. Tissue obtained at biopsy can also support molecular characterization relevant to tumor biology and to the role of human papillomavirus in carcinogenesis. The significance of cervical biopsy lies in enabling early detection and accurate staging, which improve treatment outcomes and inform prevention. Sub-areas include colposcopy-directed sampling, cervical cytology and its correlation with histology, grading of intraepithelial neoplasia, the HPV basis of cervical disease, and the integration of biopsy findings into screening and treatment programs.
Research published in this journal
5 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Cervico-Vaginal Smear Abnormalities in a Patient with Pemphigus Vulgaris
Comparative Survival Assessment of Two-Dimension (2D) vs Three-Dimension (3D) Brachytherapy Treatment in Cervical Cancer: A Retrospective Case Control Study
Early Detection of Post-transplant Lymphoproliferative Disorder by Head and Neck Manifestations
Uptake of Cervical Cancer Screening Among Female Staff at the University College Hospital, Ibadan
How this research is being cited
The 5 articles above have been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.
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2016 · Journal of Hematology and Oncology Research
A sample of recent works citing this journal's research on Cervical Biopsy, linking to each citing work.