Research Topic · Peer-Reviewed

Crohn s Disease

Crohn's disease is a chronic inflammatory bowel disease marked by transmural, often granulomatous inflammation that may involve any part of the gastrointestinal tract, characteristically in a segmental, discontinuous distribution with predilection for the terminal ileum and colon. It results from a dysregulated immu…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 39× across the literature 🗓 Reviewed July 2026

Overview

Crohn's disease is a chronic inflammatory bowel disease marked by transmural, often granulomatous inflammation that may involve any part of the gastrointestinal tract, characteristically in a segmental, discontinuous distribution with predilection for the terminal ileum and colon. It results from a dysregulated immune response to the gut microbiota in genetically predisposed individuals, shaped by environmental influences and impaired epithelial barrier function, and follows a relapsing-remitting course over many years. Typical manifestations include abdominal pain, persistent diarrhea, weight loss, fever, and fatigue, with complications such as strictures, fistulae, and abscesses arising from the depth and chronicity of inflammation. Diagnosis combines endoscopic, histologic, and imaging assessment, including magnetic resonance enterography and computed tomography to map disease extent and detect penetrating or obstructing complications. There is no definitive cure; management spans anti-inflammatory and immunomodulatory drugs, biologic agents, nutritional therapy with elemental and peptide-based formulas, and surgery, while inflammatory mediators are investigated as therapeutic targets. The research reflected here includes MR-enterography and CT-based diagnosis, identification of actionable imaging findings, granulomatous gastritis, candidate adjuvant therapies for intestinal bowel disease, and dietary interventions in gastrointestinal disease. The journal publishes peer-reviewed studies on the diagnosis, imaging, and treatment of inflammatory bowel disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Capsaicin: A Potential Therapy Adjuvant for Intestinal Bowel Disease

I Alvarez-Leite JacquelineCorresponding author
Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerias, Brazil.
Exact topic Digestive Disorders And Diagnosis Cited by 11 doi:10.14302/issn.2574-4526.jddd-19-3063

How this research is being cited

The 12 articles above have been cited 39 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Crohn s Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Antibiotic Research.

Journal editorial board
Tonmoy Debnath · Taiwan Haihong Hao · United States Tauqeer Hussain Mallhi · Australia

This page summarises published research for orientation; it is not medical or professional advice.