Acute coronary syndrome is a spectrum of conditions caused by the sudden reduction of blood flow through a coronary artery, usually when an atherosclerotic plaque ruptures and a thrombus forms over it. It encompasses unstable angina, non-ST-elevation myocardial infarction (NSTEMI), and ST-elevation myocardial infarc…
Acute coronary syndrome is a spectrum of conditions caused by the sudden reduction of blood flow through a coronary artery, usually when an atherosclerotic plaque ruptures and a thrombus forms over it. It encompasses unstable angina, non-ST-elevation myocardial infarction (NSTEMI), and ST-elevation myocardial infarction (STEMI), distinguished by the electrocardiogram and by biomarkers of myocardial injury such as cardiac troponin. The shared mechanism is an abrupt mismatch between myocardial oxygen demand and supply that, if unrelieved, leads to irreversible necrosis of heart muscle. Prompt recognition and reperfusion, by percutaneous coronary intervention or fibrinolysis, together with antiplatelet and anticoagulant therapy, are central to limiting infarct size and mortality. Research in this area examines the localization of the angina-related artery from the admission electrocardiogram in unstable angina and NSTEMI, and reports outcomes of percutaneous coronary intervention in elderly patients with ischaemic heart disease. Related work addresses genetic polymorphisms influencing coronary heart-disease risk, the cardiovascular effects of smoking and vaping, and renal function in the setting of acute myocardial infarction, reflecting the comorbidities and risk factors that shape prognosis. Anticoagulation around cardiac procedures and markers of oxidative and inflammatory stress further connect the syndrome to its pathophysiology, prevention, and acute and longer-term management.
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 9 articles above have been cited 32 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Acute Coronary Syndrome, linking to each citing work.