International Journal of Pain Management

International Journal of Pain Management

International Journal of Pain Management – About

Open Access & Peer-Reviewed

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About the International Journal of Pain Management

Advancing understanding of pain pathophysiology through peer-reviewed research on molecular mechanisms, disease pathways, biomarker discovery, and translational science.

Illuminating the Molecular Foundations of Pain

The International Journal of Pain Management (IJP) (ISSN 2688-5328) is a peer-reviewed, open-access journal dedicated to publishing high-quality research that elucidates the pathophysiological mechanisms underlying pain disorders. Our mission is to advance scientific understanding of how pain develops, persists, and manifests at molecular, cellular, and systems levels.

IJP provides a rigorous platform for researchers investigating pain pathogenesis, signaling pathways, neurobiological mechanisms, biomarker identification, disease models, and molecular targets. By disseminating mechanistic insights and translational discoveries, we bridge laboratory science with the foundational knowledge that informs future therapeutic development.

Published by Open Access Pub and committed to COPE ethical standards, IJP ensures rapid peer review, transparent editorial processes, and global accessibility under Creative Commons Attribution (CC BY 4.0) licensing.

12-18 Days to First Decision
Open Access Publishing
Global Editorial Board
Rigorous Peer Review
Scope and Research Focus

IJP publishes original research, systematic reviews, and methodological papers that advance mechanistic understanding of pain disorders. Our scope emphasizes pathophysiological discovery rather than clinical treatment protocols, focusing on the biological underpinnings that drive pain states.

Molecular Pain Mechanisms

Ion channel function, receptor pharmacology, neurotransmitter systems, gene expression profiling, and intracellular signaling cascades in nociception.

Neurobiological Pathways

Central sensitization mechanisms, dorsal horn processing, descending modulation systems, neuroplasticity in chronic pain, and brain circuit alterations.

Inflammatory & Immune Mechanisms

Cytokine signaling, neuroimmune interactions, glial cell activation, peripheral sensitization, and inflammatory mediator cascades in pain pathogenesis.

Biomarker Discovery

Identification and validation of molecular, genetic, proteomic, and metabolomic biomarkers for pain phenotyping and mechanistic classification.

Disease Models & Pathogenesis

Animal models of neuropathic, inflammatory, visceral, and cancer-related pain; cellular models; and translational model validation studies.

Genetic & Epigenetic Factors

Genetic polymorphisms influencing pain susceptibility, epigenetic modifications in chronic pain states, and heritable risk factors.

Neurotransmitter & Receptor Systems

Opioid, glutamate, GABA, serotonin, norepinephrine, and purinergic receptor mechanisms; transporter function; and synaptic modulation.

Cellular & Tissue Pathology

Nerve injury responses, Wallerian degeneration, ectopic activity generation, neuroma formation, and tissue-level pathological changes.

Systems Neuroscience Approaches

Functional imaging correlates of pain processing, network connectivity alterations, computational modeling, and systems-level circuit analysis.

Scope Clarification: IJP prioritizes mechanistic research that explains how pain works at molecular and cellular levels. Submissions focused primarily on clinical management, treatment protocols, patient outcomes, or therapeutic guidelines should be directed to clinically oriented pain journals. We encourage translational studies that connect basic science discoveries to pathophysiological understanding.
Why Publish with IJP?

Researchers choose IJP for its commitment to scientific rigor, editorial responsiveness, and global reach. Our open-access model ensures your mechanistic discoveries are immediately available to the international research community without subscription barriers.

  • Rapid Peer Review: Average first decision in 12-18 days with constructive feedback from expert reviewers in pain pathophysiology.
  • Open Access Visibility: CC BY 4.0 licensing enables unrestricted sharing, citation, and integration into educational materials worldwide.
  • Rigorous Scientific Standards: Editorial board of internationally recognized pain researchers ensures methodological excellence and reproducibility.
  • Global Indexing: Articles indexed in major databases including Google Scholar, ResearchGate, and discipline-specific repositories.
  • Ethical Publishing Practices: COPE-aligned policies on data transparency, conflict of interest disclosure, and research integrity.
  • Author Support Services: Professional language editing, figure preparation guidance, and submission assistance available.
  • No Length Restrictions: Comprehensive mechanistic studies encouraged; supplementary data hosting for complex datasets.
  • Transparent APCs: Clear pricing with waivers available for researchers from low-income countries and early-career investigators.
Submission and Editorial Process

IJP welcomes submissions from researchers worldwide. Manuscripts undergo initial screening for scope alignment and methodological soundness, followed by rigorous peer review by experts in relevant areas of pain pathophysiology.

How to Submit: Authors can submit manuscripts through our online submission portal or via email to [email protected]. Detailed formatting guidelines, ethical requirements, and preparation instructions are available in our Instructions for Authors.
Manuscript Types

IJP publishes diverse research formats to accommodate different types of mechanistic investigations:

  • Original Research Articles: Novel experimental findings on pain mechanisms, pathways, or biomarkers (typically 3,000-6,000 words).
  • Systematic Reviews: Comprehensive syntheses of mechanistic literature using systematic methodology and transparent reporting.
  • Methodological Papers: New techniques, model validation studies, or analytical approaches for pain pathophysiology research.
  • Brief Reports: Concise communications of preliminary findings, negative results, or replication studies (1,500-2,500 words).
  • Perspective Articles: Expert analyses of emerging mechanistic concepts, translational opportunities, or methodological challenges.
Peer Review Standards

All submissions receive single-blind peer review by at least two independent experts. Reviewers assess:

  • Scientific rigor and experimental design quality
  • Appropriateness of pain models and mechanistic assays
  • Statistical methodology and data interpretation
  • Reproducibility, transparency, and adherence to reporting guidelines
  • Novelty and significance of mechanistic insights
  • Clarity of presentation and logical organization
Editorial Board Excellence

Distinguished International Leadership

IJP's editorial board comprises leading researchers in pain neuroscience, molecular biology, pharmacology, and translational medicine. Our editors bring expertise across nociception mechanisms, central nervous system pathophysiology, neuroimmunology, and biomarker science.

Board members are selected based on research impact, methodological expertise, and commitment to advancing mechanistic understanding of pain disorders. They guide editorial decisions, mentor emerging researchers, and ensure the journal maintains the highest scientific standards.

Open Access and Author Rights

IJP operates under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, granting authors maximum control and readers unrestricted access. Published articles can be:

  • Freely downloaded, shared, and distributed without permission
  • Adapted, translated, or built upon with proper attribution
  • Integrated into teaching materials, grant applications, and institutional repositories
  • Cited in derivative works and systematic reviews
Article Processing Charges: As an open-access journal, IJP charges a publication fee for accepted manuscripts to cover peer review, editorial services, production, and hosting. Detailed APC information, institutional discounts, and waiver eligibility criteria are available on our Article Processing Charges page.
Indexing and Discoverability

IJP articles are indexed and archived across multiple platforms to maximize visibility and long-term accessibility:

  • Academic Databases: Google Scholar, ResearchGate, Academia.edu, Semantic Scholar
  • Institutional Repositories: Compatible with university and funding agency mandates
  • Specialized Indexes: Pain research databases and neuroscience collections
  • DOI Registration: Permanent identifiers via Crossref for reliable citation tracking
  • ORCID Integration: Author profile linking for research impact tracking

Submit Your Pain Mechanism Research to IJP

Join our global community of researchers advancing mechanistic understanding of pain pathophysiology. Share your discoveries through rigorous peer review, rapid publication, and open-access dissemination.

Contact Information: For inquiries about manuscript suitability, editorial policies, or submission procedures, please contact the editorial office at [email protected]. We respond to all correspondence within 48 hours.