Acute pancreatitis is the sudden onset of inflammation of the pancreas, in which premature activation of digestive enzymes leads to autodigestion of pancreatic tissue, local injury, and a systemic inflammatory response. The most common causes are gallstones and excessive alcohol consumption, with additional triggers…
Acute pancreatitis is the sudden onset of inflammation of the pancreas, in which premature activation of digestive enzymes leads to autodigestion of pancreatic tissue, local injury, and a systemic inflammatory response. The most common causes are gallstones and excessive alcohol consumption, with additional triggers including hypertriglyceridemia, certain medications, trauma, infection, and anatomical or metabolic disorders. The disease ranges from a mild, self-limiting interstitial form to severe necrotizing pancreatitis complicated by pancreatic necrosis, fluid collections, infection, and multiorgan failure. Patients typically present with acute upper abdominal pain, often radiating to the back, accompanied by nausea and vomiting, and diagnosis rests on a combination of clinical features, elevated serum pancreatic enzymes, and cross-sectional imaging. Severity assessment and prognosis draw on clinical scoring systems, biochemical markers, and radiological grading such as computed tomography severity indices, which guide monitoring and intervention. Management centers on supportive care, including fluid resuscitation, analgesia, and nutritional support, with treatment of the underlying cause and intervention for complications when needed. The scholarship gathered here reflects these themes, including correlation of a modified computed tomography severity index with biochemical markers and a clinical account of groove pancreatitis, illustrating how imaging, laboratory findings, and clinical evaluation together inform diagnosis, risk stratification, and care.
6 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 6 articles above have been cited 3 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Acute Pancreatitis, linking to each citing work.