Acetic acid is a simple carboxylic acid with the chemical formula CH₃COOH, widely recognized as the main component of vinegar and an important reagent in chemical synthesis and analysis. Research published in New Developments in Chemistry demonstrates the compound's diverse applications across pharmaceutical analysi…
Acetic acid is a simple carboxylic acid with the chemical formula CH₃COOH, widely recognized as the main component of vinegar and an important reagent in chemical synthesis and analysis. Research published in New Developments in Chemistry demonstrates the compound's diverse applications across pharmaceutical analysis, organic synthesis, and biological research. Studies have employed acetic acid as a mobile phase component in high-performance liquid chromatography for quantifying pharmaceutical compounds including atorvastatin calcium and imipramine hydrochloride in commercial formulations. The compound serves as a solvent and reaction medium in synthetic chemistry, including work on glycosyl amide synthesis through hydrolysis and Ritter-like reactions of carbohydrates. In biological contexts, acetic acid appears in extraction and analytical procedures for evaluating phytochemical constituents with antimicrobial properties, studying alkaloid production in plant cell cultures, and assessing bioactive compounds from natural sources. Its role extends to spectroscopic studies where acetic acid functions as a solvent for characterizing organic molecules. The breadth of these applications underscores acetic acid's fundamental importance as both an analytical tool and a versatile chemical reagent across pharmaceutical, synthetic, and natural product research domains.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 71 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Acetic Acid, linking to each citing work.