Overview
A retrospective study is an observational research design that looks backward in time, using existing records—medical charts, registries, autopsy findings, pathology archives, or imaging—to examine associations between prior exposures or characteristics and subsequent outcomes. Unlike prospective studies, it analyzes events that have already occurred, which makes it efficient for investigating rare conditions, long latency periods, and questions where randomized experimentation is impractical, while remaining susceptible to selection and information bias and to incomplete documentation. Retrospective designs include case series, retrospective cohort, and case-control analyses. Research using this approach spans many clinical fields: multi-year analyses of syphilis and associated comorbidities, autopsy series linking thymic hypertrophy to sudden unexpected death, comparisons of brachytherapy techniques in cervical cancer, evaluation of gallbladder mucosal changes by stone type, hospital-based studies of liver disease trends, transplant outcomes, prostate biopsy findings, and anatomical risk factors in implant dentistry. Such studies generate hypotheses, quantify disease burden and trends, identify prognostic and risk factors, and inform the design of subsequent prospective work. Rigorous case definition, consistent data abstraction, and appropriate statistical adjustment strengthen their validity. The journal publishes peer-reviewed retrospective analyses across these diagnostic, therapeutic, and epidemiological contexts.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Thymic Hypertrophy and Sudden Unexpected Death In Adults –A Retrospective Study Of 56 Autopsy Cases
Chemotherapy after whole-brain radiotherapy: a prognostic factor for metastatic breast cancer
Comparative Survival Assessment of Two-Dimension (2D) vs Three-Dimension (3D) Brachytherapy Treatment in Cervical Cancer: A Retrospective Case Control Study
Evaluation of Gall Bladder Mucosal Changes in Relation to the Type of Stones in Patients Undergoing Laparoscopic Cholecystectomy: A Retrospective Study of 394 Patients
Liver Disease: A Retrospective Hospital Based Study in Addis Ababa-Ethiopia
Magnitude and Trends of Chronic Liver Disease: A Retrospective Hospital Based Study in Eastern Amhara Region, Northeast Ethiopia
Living Kidney Transplant: The Influence of Intra-Operative Hemodynamics on Delayed Graft Function
Anatomical Risk Factors Associated with Immediate Extraction Placement in the Posterior Maxilla: A Human Retrospective Cone-Beam Study
Stratified Analysis of Factors Associated With Mortality in Patients With COVID-19 Based on Cancer and Diabetes
Juvenile Idiopathic Arthritis in a New Rheumatology Clinic in Nigeria
Markers for Significant or High-Grade Prostate Cancer in Patients over 75 Years Undergoing Prostatic Biopsy
How this research is being cited
The 12 articles above have been cited 20 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · BioMed Research International
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2025 · BMC Gastroenterology
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2025 · BMC Gastroenterology
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2024 · Risk Management and Healthcare Policy
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2024 · Journal of Clinical Medicine of Kazakhstan
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2024 · Journal of Clinical Medicine of Kazakhstan
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2024 · Risk Management and Healthcare Policy
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2024 · Research Square (Research Square)
A sample of recent works citing this journal's research on Retrospective Study, linking to each citing work.