Research Topic · Peer-Reviewed

Signaling Cell

Cell signaling is the system of molecular communication by which cells detect, transmit, and respond to information from their environment and from one another, coordinating development, homeostasis, immunity, and tissue repair. A signaling cell releases or presents a signal, typically a hormone, growth factor, cyto…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 27× across the literature 🔖 ISSN 2640-6403 🗓 Reviewed July 2026

Overview

Cell signaling is the system of molecular communication by which cells detect, transmit, and respond to information from their environment and from one another, coordinating development, homeostasis, immunity, and tissue repair. A signaling cell releases or presents a signal, typically a hormone, growth factor, cytokine, neurotransmitter, or other ligand, which is recognized by specific receptors on a target cell and converted into an intracellular response. Signaling is classified by range and mode as endocrine, paracrine, autocrine, juxtacrine, and synaptic, and receptors range from cell-surface G-protein-coupled receptors, receptor tyrosine kinases, and ion channels to intracellular nuclear receptors. Ligand binding triggers transduction cascades involving second messengers, protein phosphorylation, and the activation of transcription factors, ultimately altering gene expression, metabolism, proliferation, differentiation, or survival. The fidelity and amplitude of these pathways are tightly regulated, and their dysregulation underlies cancer, immune dysfunction, and degenerative disease. Key concepts include signal amplification, feedback regulation, cross-talk between pathways, and the spatial and temporal control of signaling networks. Methodologically the field employs molecular and computational analysis of pathways, transcription-factor binding, and signaling molecules. The journal publishes peer-reviewed research relevant to cellular signaling and intercellular communication, addressing the molecular mechanisms by which signals govern cell behavior in health, disease, and regenerative processes.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Robust Sampling of Defective Pathways in Parkinson Disease

Luis Fernández-Martínez JuanCorresponding author
Group of Inverse Problems, Optimization and Machine Learning. Department of Mathematics. C/ Federico García Lorca, 18. 33007 Oviedo. University of Oviedo. Spain
Medical Informatics and Decision Making Cited by 2 doi:10.14302/issn.2641-5526.jmid-18-2529

How this research is being cited

The 12 articles above have been cited 27 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Signaling Cell, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Tissue Repair and Regeneration (ISSN 2640-6403).

Journal editorial board
Walid Rachidi · France Ilaria Baldelli · Italy Costica Aloman · United States

This page summarises published research for orientation; it is not medical or professional advice.