Recently Published Articles
A Solitary Necrotic Lesion in A Man with Acute Myeloid Leukemia and neutropenia
Abstract:
A case of a solitary necrotic cutaneous lesion in a neutropenic patient with acute myeloid leukemia is described. The report discusses infectious and non‑infectious differentials, work‑up under immunosuppression, and targeted management.
Endothelial Function in Stroke Subtypes Using Endopat Technology
Abstract:
Background. Endothelial function is characterized by the vasodilator capacity of blood vessel smooth muscle cells mediated by nitric oxide. Some studies have shown an inverse association between the endothelial function and the carotid intima-media thickness (IMT). The relationship between endothelial dysfunction and stroke based on several studies has shown that is altered in all stroke subtypes especially lacunar strokes. Methods. We aimed to investigate endothelial function by EndoPAT device in relation to stroke subtypes. We investigate too the correlations between endothelial function and IMT and we study possible interactions with age, sex, traditional risk factors and severity of stroke. Subsequent patients with acute ischemic stroke were enrolled. They were divided according with the etiological mechanism of stroke (TOAST classification). Endothelial function was assessed with finger plethysmography by the EndoPAT device that gave Reactive Hyperemia Index ...
RETRACTED: In-Stent Thrombosis in the Middle Cerebral Artery (MCA): A Case Report
Abstract:
This article has been retracted on November 20, 2015. VIEW THE RETRACTION NOTICE ( In-stent thrombosis (IST) is a complication of angioplasty and stenting, especially in the vessels with smaller diameter. We present a case of subacute IST after stenting treatment of an isolated higher stenosis of the right middle cerebral artery (MCA). Analysis of clinical features and emergent brain image helped to indicate the pathophysiological mechanism underlining the symptoms of this patient. Emergent Transcranial Doppler (TCD) helped to evaluate the compensatory collateral circulation and provided good supporting evidence in deducing the mechanism of IST. Slightly larger size of the implanted stent that caused dissection or vascular endothelium injury was presumed in this patient. Persistent evidence o...
Refractory Anaemia with Hyperoxalurea
Abstract:
We report 2 cases of primary hyperoxalurea who presented with refractory anaemia, nephrolithiasis, renal failure warranting repeated renal transplantation in one of the cases. Renal biopsy of the patients revealed crystals of calcium oxalate in the tubules. The same crystals were also visualized in bone marrow biopsy which confirmed the diagnosis of systemic oxalosis. We conclude that Primary hyperoxalurea may rarely cause anemia secondary to calcium oxalate crystal deposition in the bone marrow.
Management of Absent Capsular Support with a new Intraocular Lens Design
Abstract:
To describe a new intraocular lens that can be implanted in case of rupture of the posterior capsule and lack of capsular support. This experimental study was carried out on ten Flanders rabbits. The right eye of each rabbit underwent intra capsular lens extraction and two peripheral iridectomies, and the new lens was implanted with an optic rest in the posterior chamber. Additionally, the haptics rest in the angle of the anterior chamber through peripheral iridectomies. Main outcome measures were lens stability inside the eye and complications regarding this technique Intraocular lenses remained in a stable position with only a mild inflammatory reaction; four eyes developed hyphema that...
Central Retinal Vein Occlusion in Hepatocellular Carcinoma
Abstract:
A 66 year old Chinese male with a medical history of hypertension, diabetes mellitus and hepatitis B carrier was diagnosed with hepatocellular carcinoma in 2009. He underwent treatment with selective internal radiation spheres and sorafenib, and multiple cycles of chemotherapeutic agents such as bevacizumab, erlotinib, OXAFI ( intravenous oxaliplatin and doxorubicin given on days 1, 8 and 15 in a 28-day cycle, a daily continuous infusion of fluorouracil and subcutaneous interferon alfa-2b 5 million units administered thrice weekly), thalidomide, capecitabine, and rapamycin over the course of four years. Along the course of treatment, he developed pulmonary embolism and was initially started on anti-coagulation. Two months later, he developed hemoptysis and the anti-coagulants were stopped. During his routine ophthalmology visit for diabetic eye evaluation, he complained of blurring of vision of his left eye for the past four to five...
Leiomyosarcoma of the Thyroid Gland: A Review of the Literature and our Experience
Abstract:
Primary thyroid leiomyosarcoma, is extremely rare, with only 19 cases reported in the literature to date. Onset of the tumor, which usually develops in only one lobe of the thyroid, is sudden and the tumor spreads rapidly to surrounding tissues. Preoperative differential diagnosis is extremely difficult. The long-term prognosis for the patient is extremely poor and unrelated to treatment. Indeed, thyroidectomy and neck dissection followed by adjuvant chemotherapy and/or radiation therapy have not been shown to affect rate of recurrence and long-term survival. The authors describe the case of a patient with leiomyosarcoma of the thyroid gland and review the relevant literature, considering the differential diagnoses and alternative treatment strategies.
Waste Clay for Biodiesel Through Base Catalyzed Transesterification of Residual Cotton Seed Oil.
Abstract:
After processing of cotton seed oil (CSO) the activated bleaching clay (ABC) is converted to low valued waste bleaching clay (WBC). The chemical composition of ABC from Mirpur, Azad Kashmir region of Pakistan is found out as; SiO2 71.34, Al2O3 15.54, CaO 2.72, MgO 1.48, Na2O 0.51, K2O 0.23, Fe2O3 0.02. The clay has bleachability (74 %) and oil retention (32.70 %) by standard method (ASTM). The cotton seed oil recovered (CSOR) with polar/nonpolar solvents (31.1-36.3 %) have different FFA values (0.2-0.85). However, lower percentage of tri-esters (88 %) was found out in dark coloured CSOR as compare to freshly n-hexane extracted CSO (92.5 %) from edible oil refinery. The lower FFA (0.2) valued CSOR with n-hexane is transesterified at optimized conditions to mono alkyl esters (CSOR-FAME). The reaction was optimised by performing series of experiments to observe molar conc., of methanol-oil (3-18:1), catalysts; NaOH, NaOCH3, KOH, KOCH3- oil (0.25-1.5), temperature (20...
Medullary Thyroid Cancer: Is the Adequacy of Pre-Operative Evaluation Influenced by Training Background?
Abstract:
Medullary Thyroid Cancer (MTC) is a rare malignancy, accounting for less than 3% of all thyroid cancers and causes significant morbidity and mortality. MTC is often due to an underlying mutation of the RET proto-oncogene, which can result in additional endocrinopathies that must be screened for pre-operatively. The project aim was to determine if surgical training background influenced patient pre-operative evaluation for MTC. A retrospective review was performed of patients undergoing thyroidectomy for MTC at a single academic institution. Patients were analyzed based on who performed the initial operative procedure, a surgeon with specific endocrine surgery training or a surgeon without. From...
Gender Differences in Adherence to Mediterranean Diet and Risk of Atrial Fibrillation.
Abstract:
Adherence to the Mediterranean Diet (MedD) is associated with a reduction of overall mortality and mortality from cardiovascular diseases and cancer. In a previous study we found a relationship between intake of antioxidant vitamins with diet and risk of atrial fibrillation (AF). The present study focuses on gender differences relative to diet and antioxidant intake in patients (pts) with a first detected episode of AF. A group of 400 pts, 205 men and 195 women, was investigated. A control group of 400 subjects, age and sex matched, was selected and compared. Nutritional parameters were assessed by a self-administered food frequency validated questionnaire (116 items) completed by an interviewer-administered 24 h diet recall. We previously constructed a MedD adherence score based on a prior s...