Research Topic · Peer-Reviewed

Cancer Cells

Cancer cells are transformed cells that proliferate in an uncontrolled, dysregulated manner, having acquired genetic and epigenetic alterations that confer self-sufficiency in growth signals, insensitivity to growth-inhibitory and apoptotic cues, replicative immortality, and the capacity to invade and metastasize. T…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 147× across the literature 🔖 ISSN 2572-3030 🗓 Reviewed July 2026

Overview

Cancer cells are transformed cells that proliferate in an uncontrolled, dysregulated manner, having acquired genetic and epigenetic alterations that confer self-sufficiency in growth signals, insensitivity to growth-inhibitory and apoptotic cues, replicative immortality, and the capacity to invade and metastasize. They evade normal checkpoints and programmed cell death, sustain angiogenesis, reprogram metabolism, and can disseminate through blood and lymphatics to seed distant sites, forming tumors and producing systemic disease. Understanding their molecular biology underpins the development of targeted and cytotoxic therapies. Research relevant to this area examines the initiation and development of sporadic non-hereditary solid cancers, apoptosis resistance and gene-expression changes in colorectal cancer cells, the role of Prostate Apoptosis Response-4 and E-cadherin in suppressing colon-cancer metastasis, transcription-factor requirements for thyroid-cancer-cell proliferation, selective cytotoxicity of natural and synthetic compounds in breast-cancer cells, oncofetal antigen biology, and minimal residual cancer-cell progression in the perioperative period. The journal publishes peer-reviewed work in Cancer Genetics And Biomarkers addressing the molecular and cellular mechanisms governing malignant cell behavior, drug response, apoptosis, and metastasis, linking experimental cell-line and mechanistic studies to strategies for selectively targeting and eliminating cancer cells across multiple tumor types.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2014

Factors that Influence Fenofibrate Effects on Cancer Cells

A. Vlahopoulos SpirosCorresponding author
Horemio Research Institute, First Department of Pediatrics, University of Athens Medical School, “Aghia Sophia” Children’s Hospital, Athens, Greece
Exact topic Hematology and Oncology Research Cited by 1 doi:10.14302/issn.2372-6601.jhor-13-362

How this research is being cited

The 12 articles above have been cited 147 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Cancer Cells, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Cancer Genetics And Biomarkers (ISSN 2572-3030).

Journal editorial board
Dr. Charlie Gourley · United Kingdom Dr. Xinyu Chen · United States Dr. Guru Prasad Maiti · United States

This page summarises published research for orientation; it is not medical or professional advice.