High-Throughput Complex-Disease Modeling for Ethical Drug Discovery: Clinical Relevance of a NAM Platform for Cancer Biomarker Development
Dillier E, Sousa R, Kluser T, et al.
Peer-reviewed · Open Access
Journal of Cancer Genetics and Biomarkers
Reading the cancer genome — from variant to biomarker to clinical decision.
JCGB publishes peer-reviewed research on the molecular genetics of cancer and the biomarkers that turn it into precision oncology — open access under CC BY, with Crossref DOIs and an international editorial board. Publishing since 2014.
What JCGB publishes
Where molecular mechanism meets biomarker translation
JCGB publishes work that connects the molecular biology of cancer to biomarkers with translational value — mechanism, discovery, and validation in one place.
MECHANISM
Molecular tumorigenesis
Oncogenic pathway dysregulation, tumor-suppressor loss, genomic instability, and the DNA-damage response.
DISCOVERY
Biomarker discovery & validation
Genomic, transcriptomic, and proteomic signatures for stratification, prognosis, and therapy selection.
LIQUID BIOPSY
ctDNA, CTCs & MRD
Circulating tumor DNA, tumor cells, exosomes, and minimal-residual-disease monitoring.
EVOLUTION
Tumor & clonal dynamics
Clonal architecture, mutational signatures, metastasis, and therapy-induced evolution.
RESISTANCE
Targets & pharmacogenomics
Druggable-target identification, acquired resistance, synthetic lethality, and response genomics.
GERMLINE
Hereditary predisposition
Inherited cancer syndromes, germline variant pathogenicity, and familial-cancer biomarkers.
EPIGENETICS
Cancer epigenetics
DNA methylation, histone and chromatin remodelling, and non-coding-RNA regulation.
MICROENV.
Tumor microenvironment
Immune, stromal, and metabolic interactions shaping progression and treatment response.
MULTI-OMICS
Functional & computational genomics
CRISPR screens, organoid and PDX models, single-cell and spatial multi-omics for precision oncology.
Why publish in JCGB
Built for cancer-genetics research, and for the people who read it
Genuinely open
Published under CC BY with copyright retained by you, so your work reaches the widest readership without paywalls.
Rigorously reviewed
Single-blind (double-blind on request), managed by an editorial board of working molecular-oncology scientists.
Read where it matters
A global audience of cancer geneticists, oncologists, and pathologists working across precision oncology.
Persistently identified
Each published article is assigned a Crossref DOI for persistent identification, linking, and citation.
Editorial oversight
An international editorial board
The journal’s current editorial board, including approved roles, affiliations and available identifiers, is maintained on the Editorial Board page.
From the journal
Selected research from JCGB
A sample of work published in JCGB — each with a permanent DOI you can follow now.
Dynamic MicroRNA Expression in Plasma of Melanoma Patients Correlates with Progression, PD-L1 Status, and Overall Survival
Degenhardt S, Bender M, Chen I-P, et al.
Targeting the Mutational Landscape of TP53 in Patients Diagnosed with Oral Cancer Living in Senegal
Sarr PD, Touré S, El Fahime E, et al.
Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco/Alcohol-Induced Head and Neck Cancer
Gupta S, Kumar P, Maini J, Bharadwaj M
Cost & permanence
Priced clearly, permanently identified
Article processing charge
USD 2,199
A single charge applies to every accepted article, whatever its type — there is no separate submission or review fee.
- Peer-review management and editorial handling
- Professional production, typesetting, and hosting
- A persistent Crossref DOI and indexing metadata
- Open-access publication under CC BY
Authors facing funding difficulties may contact the editorial office before submission to enquire about current waiver options and eligibility.
Full charge & waiver details →Identifiers & discovery
What JCGB states plainly, and can verify:
- Every article carries a permanent Crossref DOI (prefix 10.14302/issn.2572-3030)
- Registered under ISSN 2572-3030 in the global ISSN Portal
- Content is discoverable through search engines and the open web
- Free to read, share, and self-archive under CC BY
- Participating in the Portico digital-preservation program
For authors
Frequently asked questions
Is my work in scope for JCGB?
JCGB publishes cancer research with a clear molecular-genetic or biomarker dimension — tumorigenesis mechanisms, biomarker discovery and validation, liquid biopsy (ctDNA, CTCs, exosomes, MRD), tumor evolution, molecular targets and resistance, hereditary cancer, epigenetics, the tumor microenvironment, and computational multi-omics. If your study links molecular findings to cancer biology or translation, it fits. See the full aims & scope →
Is JCGB peer reviewed, and how?
Yes. Peer review is Single-blind (double-blind on request), managed by the journal's international editorial board, with reviewers matched to the molecular and clinical subject matter of each submission.
What is the APC, and what does it cover?
The article processing charge is USD 2,199 and is applicable to each accepted article, with no separate submission or review charge. It funds peer-review management, professional production, a Crossref DOI, indexing metadata, and open-access hosting. Review the current Article Processing Charges page for payment and waiver information.
Is JCGB open access, and who holds copyright?
JCGB is fully open access. Every article is published under a Creative Commons Attribution (CC BY) license and authors retain copyright, so anyone can read, share, and build on your work with proper attribution.
How do I submit a manuscript?
ManuscriptZone is JCGB’s primary and recommended submission system. Authors may also submit through the Simple Manuscript Submission form or by email to the editorial office. Please use only one submission method for each manuscript. View submission options →
How are JCGB articles preserved and discovered?
Each published article is assigned a Crossref DOI for persistent identification, linking, and citation. Articles are discoverable through search engines and the open web, and the CC BY license lets anyone find, read, and cite them without restriction. JCGB also participates in the Portico digital-preservation program.
Submit to JCGB