Dr. Xiou Cao PhD

Dr. Xiou Cao is an expert in Neuroimmunology and Host-Pathogen Interactions, leveraging molecular genetics to understand fundamental disease mechanisms. His research has focused on the critical role of the nervous system in regulating immunity, including identifying how neural circuits, like dopaminergic signaling, modulate immune responses. He possesses specialized expertise in protein engineering and antibody discovery within infectious and cardiometabolic diseases. His work is essential for developing novel diagnostics and therapeutic interventions in biomedical science.

Education Details

Dr. Cao's academic background includes significant training at major US research institutions:

• PhD: (Department of Molecular Genetics and Microbiology 2012-2017)
• Postdoctoral Scholar: Department Of Medicine (Stanford University School Of Medicine, 2018).
• Research Assistant & Postdoctoral Associate: Department Of Molecular Genetics And Microbiology (Duke University School Of Medicine, 2013-2017).

Professional Background

His professional career spans both top-tier academic research and major pharmaceutical innovation centers:

• Senior Scientist, Biomolecular Technologies (Current, Since Jan 2022) - Novo Nordisk Research Centre China.
• Scientist, Disease Biology (2019-2020) - Global Health Drug Development Institute, Beijing.

Current Research Projects

His current research efforts are applied toward drug discovery and technology development:

• Protein Engineering And Antibody Discovery: Focusing on molecular biology methods for developing immunotherapeutics for inflammation and infectious diseases

Academic Profiles of Dr. Xiou Cao

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Dr. Cao's publications reflect influential original discoveries regarding the complex interplay between the nervous system, host immunity, and pathogen persistence.

The list of recent publications of Dr. Xiou Cao is listed below:
 

• Cao, X., et al. (2019). Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis. Science Translational Medicine, 11(488). DOI: 10.1126/scitranslmed.aau9748.
• Cao, X., et al. (2019). Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection. Science, 363(6429), 835-839. DOI: 10.1126/science.aat9691.
• Cao, X., Kajino-Sakamoto, R., Doss, A., & Aballay, A. (2017). Distinct roles of sensory neurons in mediating pathogen avoidance and neuropeptide-dependent immune regulation. Cell Reports, 21(6), 1442-1451. DOI: 10.1016/j.celrep.2017.10.050.
• Cao, X., & Aballay, A. (2016). Neural Inhibition of Dopaminergic Signaling Enhances Immunity in a Cell-Non-autonomous Manner. Current Biology, 26(17), 2329-2334. DOI: 10.1016/j.cub.2016.06.036.
• Wang, Y., Pannuri, A. A., Ni, D., Zhou, H., Cao, X., et al. (2016). Structural Basis for Translocation of a Biofilm-supporting Exopolysaccharide across the Bacterial Outer Membrane. Journal of Biological Chemistry, 291(19), 10046-10057. DOI: 10.1074/jbc.M115.711762.

Last updated on September 30, 2025