Dr. Amgad M. Rabie

Address:

Faculty of Pharmacy, Tanta University, El-Giesh Street, Tanta, 31527, Gharbia Governorate, Egypt

Academic Metrics

• h-index: 19
• i-10 index: 28
• Total Citations: 1129

Research Interests:

• Medicinal Chemistry

• Drug Design and Discovery

• Anticancer Drug Development

• Antimicrobial and Antiviral Agents

• Heterocyclic Chemistry

• Computational Chemistry & Molecular Modeling

• Green Chemistry in Organic Synthesis

• Structure-Activity Relationship (SAR) Studies

• ADMET Prediction

Biography:

Dr. Amgad M. Rabie is a distinguished academic and researcher serving as an Associate Professor in the Department of Pharmaceutical Medicinal Chemistry at Tanta University, Egypt. His work is primarily focused on the frontier of drug discovery and development, with a specialization in the design, synthesis, and biological evaluation of novel heterocyclic compounds. Dr. Rabie's research program strategically targets the creation of potent therapeutic agents to combat pressing global health challenges, including cancer, microbial infections, and viral diseases. He integrates sophisticated computational chemistry methodologies, such as molecular docking, pharmacophore modeling, and ADMET prediction, to rationalize drug design and optimize lead compounds. His scholarly contributions are significant, demonstrated by a prolific publication record in high-impact international journals. Dr. Rabie is dedicated to advancing the field of medicinal chemistry through innovative research and the mentorship of future pharmaceutical scientists.

Education Details:

• PhD in Pharmaceutical Medicinal Chemistry, Tanta University, Egypt (2015)

• M.Sc. in Pharmaceutical Medicinal Chemistry, Tanta University, Egypt (2012)

• B.Sc. in Pharmaceutical Sciences, Tanta University, Egypt (2007)

Professional Background:

• Associate Professor, Department of Pharmaceutical Medicinal Chemistry, Tanta University (2020–Present)

• Lecturer (Assistant Professor), Department of Pharmaceutical Medicinal Chemistry, Tanta University (2015–2020)

• Assistant Lecturer, Department of Pharmaceutical Medicinal Chemistry, Tanta University (2012–2015)

• Demonstrator, Department of Pharmaceutical Medicinal Chemistry, Tanta University (2008–2012)

Achievements:

• Recipient of the Tanta University Encouragement Award for Medical Sciences (2020)

Current Research Projects: His current research focuses on the development of multi-target anticancer agents by designing hybrid molecules that act on key signaling pathways like EGFR and VEGFR. He is also exploring novel scaffolds for potent antibacterial and antifungal agents to combat drug-resistant strains. A significant part of his work involves using green chemistry principles for the eco-friendly synthesis of these bioactive compounds.

 

Academic Profiles of Dr. Amgad M. Rabie:

• ORCID: https://orcid.org/0000-0002-9213-3715

• Scopus: https://www.scopus.com/authid/detail.uri?authorId=55500138300

• Google Scholar: https://scholar.google.com/citations?user=7Jc3T-kAAAAJ

• Web of Science: https://www.webofscience.com/wos/author/record/AAG-3622-2019

• ResearchGate: https://www.researchgate.net/profile/Amgad-Rabie-2

• LinkedIn: https://eg.linkedin.com/in/amgad-rabie-26829792

• University Profile: http://pharm.tanta.edu.eg/en/staff_search_details.aspx?id=1285

• Semantic Scholar: https://www.semanticscholars.org/author/Amgad-M.-Rabie/47854812

Publications:

Dr. Rabie maintains a strong publication output, with his recent work appearing in prominent journals focused on medicinal chemistry and pharmacology. His latest research continues to explore novel heterocyclic compounds as potent agents for cancer therapy and in combating infectious diseases.

List of 5 Recent Publications:
 

1. Abdel-Aziz, M., Moqbel, M. S., El-Zahabi, H. S. A., & Rabie, A. M. (2024). Design, synthesis, biological evaluation and molecular modeling of novel quinoline-based hydrazones as potent anticancer agents. Journal of Molecular Structure, 1303, 137497. DOI: https://doi.org/10.1016/j.molstruc.2023.137497
2. El-Gazzar, M. G., Fawzy, N. M., Rabie, A. M., & Nossier, E. S. (2024). Discovery of novel 1, 3, 4-oxadiazole-based scaffolds as promising antimicrobial agents: design, synthesis, biological evaluation and molecular docking study. RSC Advances, 14(14), 9831-9848. DOI: https://doi.org/10.1039/D4RA00543D
3. Rabie, A. M., El-Gazzar, M. G., & Fawzy, N. M. (2024). Novel chromone-based N-aryl pyrazoles as potential antimicrobial agents: Design, synthesis, biological evaluation, and molecular docking studies. Journal of Molecular Structure, 1296, 136848. DOI: https://doi.org/10.1016/j.molstruc.2023.136848
4. El-Sayed, M. A., Rabie, A. M., & Abdel-Aziz, M. (2023). Design, synthesis, biological evaluation and molecular modeling of novel quinoline-thiazole hybrids as potential anticancer agents. Bioorganic Chemistry, 141, 106886. DOI: https://doi.org/10.1016/j.bioorg.2023.106886
5. Rabie, A. M., & Abdel-Aziz, M. (2023). Recent advances in the medicinal chemistry of quinoline-based anticancer agents (2018–2023). RSC Medicinal Chemistry, 14(12), 2272-2311. DOI: https://doi.org/10.1039/D3MD00378A

 

Last Updated on October 09, 2025