Journal of Alzheimer's Research and Therapy

Journal of Alzheimer's Research and Therapy

Current Issue Volume No: 1 Issue No: 1

Research-article Article Open Access
  • Available online freely Peer Reviewed
  • Early Prediction Of Alzheimer’s Disease Using OCT Imaging Technique

    C S Sandeep 1
        Kumar A Sukesh 2     Mahadevan K 3     P Manoj 4    

    1 Research Scholar, CET, Trivandrum, University of Kerala 

    2 Research Guide CET, Trivandrum University of Kerala 

    3 Professor Ophthalmology SGMC&RF, Kerala 

    4 Professor Neurology SGMC&RF, Kerala 

    Abstract

    Alzheimer s Disease (AD) is one amongst the overwhelming types of dementia that distresses the brain nerve cells leading to a perpetual loss in memory and creating a lot of difficulties for the family members in caretaking. The prediction of the disease at an earlier stage is a common problem. The most prevalent imaging modalities used for diagnosing AD are Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT). They can provide valuable information regarding the changes in internal and external brain regions and activities for diagnosing AD. But the relevant studies made on retina reveals that in addition to brain changes there are some variations on the retina layers of the AD patients. Therefore, the retina can be used as a biomarker for diagnosing AD. There are different techniques available for an eye examination. Most noticeable of them are Fundus Imaging and Optical Coherence Tomography (OCT). In this paper, we have focused on OCT retinal images of AD patients for the early diagnosis of AD.

    Author Contributions
    Received Feb 12, 2019     Accepted Apr 09, 2019     Published Apr 19, 2019

    Copyright© 2019 C S Sandeep, et al.
    License
    Creative Commons License   This work is licensed under a Creative Commons Attribution 4.0 International License. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    Competing interests

    The authors have declared that no competing interests exist.

    Funding Interests:

    Citation:

    C S Sandeep, Kumar A Sukesh, Mahadevan K, P Manoj et al. (2019) Early Prediction Of Alzheimer’s Disease Using OCT Imaging Technique Journal of Alzheimer's Research and Therapy. - 1(1):15-24
    DOI 10.14302/issn.2998-4211.jalr-19-2658
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