Instructions For Author

Submission guidance for Journal of Alzheimer's Research and Therapy (JALR) to help authors publish with clarity, accuracy, and impact.

Organize your manuscript clearly so reviewers and readers can follow the study logic. Most research submissions should include the following sections.

• Title: Concise and descriptive, highlighting the main outcome or population.
• Abstract: Structured abstract summarizing objectives, methods, results, and conclusions.
• Keywords: 4 to 7 keywords that improve indexing and discovery.
• Introduction: Context, rationale, and study objectives.
• Methods: Study design, participants, procedures, and statistical analysis.
• Results: Clear presentation of findings with supporting tables and figures.
• Discussion: Interpretation, limitations, clinical relevance, and future directions.
• Conclusion: Key takeaways aligned with the study objectives.

Use clear headings, standard terminology, and consistent units. Ensure all figures and tables are cited in order of appearance. For supplementary files, include a brief description in the main text.

• Use standard scientific abbreviations and define them at first use.
• Provide a list of abbreviations if the manuscript includes many specialized terms.
• Report statistical methods in sufficient detail for replication.
• Include effect sizes and confidence intervals where appropriate.
• Use high resolution images and include scale bars for microscopy or imaging outputs.

JALR does not impose strict word limits for most article types, but submissions should be concise and focused. Ensure the introduction provides context without excessive background, and the discussion interprets results without repeating the results section. Use active voice where possible and keep terminology consistent throughout the manuscript.

For systematic reviews and meta analyses, include a structured search strategy, database coverage, and selection flow. For short communications, focus on the core result and limit the number of figures and tables to what is essential for interpretation.

Tables and figures should communicate key findings at a glance and should not duplicate text content. Provide clear captions, define abbreviations, and include units. For image based data, indicate acquisition methods and processing steps.

• Submit figures in high resolution formats and avoid excessive compression.
• Ensure figure panels are labeled consistently and match in text references.
• Provide raw data where required and note any image adjustments.
• Supplementary files should be referenced in the manuscript with a clear description.

Provide enough detail for a qualified reader to understand your analysis. This includes study design, primary and secondary endpoints, software used, and model assumptions. Report exact p values where possible and explain how missing data were handled.

For clinical and longitudinal studies, describe sample size calculations and justify the analysis plan. For multi site or multi cohort studies, clarify harmonization methods and specify any sensitivity analyses performed.

Journal of Alzheimer's Research and Therapy requires confirmation of ethical review for all studies involving human participants, animals, or sensitive data. Include the name of the approving ethics committee, reference number, and a statement of informed consent where applicable.

For clinical case reports, obtain patient consent and anonymize identifiers. If consent cannot be obtained, authors must explain the circumstances and provide documentation as required.

Clinical trials must be registered in a recognized public registry before participant enrollment. Provide the registry name and registration number in the manuscript. If a study was not registered prospectively, explain the reason in the cover letter and within the methods section.

JALR considers manuscripts previously shared as preprints, provided authors disclose the preprint DOI or URL at submission. Updates from preprint to published article should highlight substantive changes such as revised analyses, additional data, or expanded discussion.

Authors may use AI tools for language refinement or formatting support, but such tools must not replace author responsibility for accuracy, interpretation, or originality. Any AI assisted tools used in the writing process should be disclosed in the acknowledgments or methods section, as appropriate.

Use established reporting guidelines to strengthen reproducibility and transparency. JALR encourages adherence to recognized standards including CONSORT for clinical trials, PRISMA for systematic reviews, STROBE for observational studies, and ARRIVE for animal research.

Include a data availability statement that describes where supporting data, code, or protocols can be accessed. If data cannot be shared due to privacy or legal restrictions, explain the reason and indicate how qualified researchers may request access.

Authors are responsible for obtaining permission to reuse copyrighted figures, tables, or instruments. Provide documentation of permission at submission and include proper attribution in the figure legends or acknowledgments.

All submissions undergo originality checks to protect scientific integrity. Manuscripts with extensive overlap, uncredited reuse, or duplicate publication will be returned without review. Ensure that reused methods text is appropriately cited and that all sources are acknowledged.

All listed authors must meet authorship criteria, participate in the work, and approve the final manuscript. Include a contributor statement outlining roles such as study design, data collection, analysis, and manuscript drafting.

Disclose all financial, institutional, or personal relationships that could influence the research. Provide funding sources and grant numbers where applicable. Transparency builds trust and protects the integrity of Alzheimer's research.

Use a consistent referencing style and ensure citations are complete and accurate. Include DOI links where available. Avoid excessive self citation and ensure that key prior work is acknowledged.

• Manuscript file in an editable format with line numbers if possible.
• Cover letter describing study significance and fit for JALR.
• Ethics approval details and informed consent statements.
• Conflict of interest and funding disclosures.
• Data availability statement and repository links.
• Figures and tables uploaded as separate files if required.

Use the cover letter to explain why your work belongs in Journal of Alzheimer's Research and Therapy and how it advances the field. Include the primary novelty, clinical implications, and any prior dissemination such as preprints. Authors may suggest qualified reviewers who are free of conflicts of interest. The editorial team may or may not use suggested reviewers, but thoughtful recommendations can accelerate review.

Journal of Alzheimer's Research and Therapy uses a single blind peer review model. Reviewers are aware of author identities to evaluate research context and related work, while author identities remain confidential to reviewers. Editorial decisions are based on scientific merit, methodological soundness, and relevance to the journal scope.

When revisions are requested, provide a point by point response to reviewer comments. Clearly indicate changes within the manuscript or highlight revisions for faster verification. Timely responses help reduce delays and improve publication timelines.

If authors believe a decision was made in error, they may submit a reasoned appeal to the editorial office. Appeals should reference reviewer comments and provide clear scientific justification. JALR evaluates appeals carefully but does not guarantee reversal of decisions.

Once accepted, manuscripts enter production for copyediting, formatting, and proof review. Authors receive proofs for final checks and must confirm accuracy before publication. Articles are typically published online first after proof approval. Article processing charges are communicated after acceptance and do not affect editorial decisions.

For submission questions, formatting support, or pre submission queries, contact [email protected]. Include your manuscript title and a short abstract for faster guidance. We are happy to help.