Editorial Board
Zakaria Abd Elmageed
Departments of Urology and Pharmacology, School of Medicine, Tulane University, 1430 Tulane Avenue · United States
Editorial leadership for Journal of Thyroid Cancer ISSN 2574-4496
Research interests
- Oncology
- Pharmacology
- Biochemistry
- Molecular Biology
Biography
- Dr. Abd Elmageed received his Ph.D. in physiology from Helwan University at Cairo in 2004 where he was also previously appointed as Assistant Professor of physiology until 2006.
- He completed his postdoctoral training at LSU Health Sciences Center, Johns Hopkins Medical School and Tulane University School of Medicine.
- His research focuses on investigating the molecular mechanisms that contribute to thyroid and prostate cancer development. His ultimate goal is to investigate the role of human stem cells in the development of the cancer disease using in vitro and in vivo models as well as human tissues.
- Exploring the role of nuclear receptors of steroidal hormones at different disease-stages and its implications in health disparity is another topic of his interest.
- He is an active member in many scientific associations and has been selected as a reviewer in several peer-reviewed journals.
- Dr. Abd Elmageed is a research instructor in the Department of Urology at Tulane University School of Medicine.
- His research interests include the cellular and molecular biology of prostate, breast and thyroid cancers. Prostate cancer is the most commonly diagnosed cancer in men and the second leading cause of cancer death in the U.S.
- Dr. Abd Elmageed’s current research focuses on elucidating the role of signaling and tumor microenvironment on adipose-derived stem cells in prostate cancer (PCa).
- He is also investigating the differential expression profile of estrogen and its receptors (Alpha/Beta) in PCa based on race, age and genetic background.
- Tissue microarray (TMA), IHC, proteomics, microRNA arrays and other molecular techniques have been used in tissue culture, on animal models and in human samples to test this hypothesis.
- Dr. Abd Elmageed’s future research goal is to elucidate the role of miRNAs delivered by cancer-related exosomes in the induction of neoplastic transformation of adipose-derived stem cells into PCa.
- He also wants to continue to study the tumor microenvironment (niche) growth releasing factors which modulate the transformation of mesenchymal stem cells in vitro and in vivo, as this has the potential for many applications in discovering new therapeutic interventions
Selected publications
- Neuroprotective Effects of Phytochemicals against Aluminum Chloride-Induced Alzheimer’s Disease through ApoE4/LRP1, Wnt3/β-Catenin/GSK3β, and TLR4/NLRP3 Pathways with Physical and Mental Activities in a Rat Model 2022 cited 68×
- Exosomes-Mediated Transfer of Itga2 Promotes Migration and Invasion of Prostate Cancer Cells by Inducing Epithelial-Mesenchymal Transition 2020 cited 60×
- Exosomes are the Driving Force in Preparing the Soil for the Metastatic Seeds: Lessons from the Prostate Cancer 2020 cited 56×
- Selenium Nanoparticles with Prodigiosin Rescue Hippocampal Damage Associated with Epileptic Seizures Induced by Pentylenetetrazole in Rats 2022 cited 33×
- Circulating microRNAs panel as a diagnostic tool for discrimination of HCV-associated hepatocellular carcinoma 2017 cited 33×
- Dysregulated gene expression predicts tumor aggressiveness in African-American prostate cancer patients 2018 cited 31×
Ranked by citation impact (Crossref) where available, newest otherwise · verified via ORCID.
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This journal is guided by Zakaria Abd Elmageed (Departments of Urology and Pharmacology, School of Medicine, Tulane University, 1430 Tulane Avenue) and a peer-review board of practising researchers. Open access, author-retained copyright (CC BY), and a clear editorial process.